Disulfiram Tablets
Product Name: Disulfiram Tablets
Common Name: Antabuse
Strength: 100 mg
Description:
Disulfiram, marketed under the trade names Antabuse and Antabus, is a medication that was discovered in the 1920s and is utilized as an adjunct in the treatment of chronic alcoholism by inducing an acute sensitivity to ethanol (alcohol). Disulfiram functions by inhibiting the enzyme acetaldehyde dehydrogenase, resulting in the immediate onset of hangover-like effects following alcohol consumption.
Indications and Usage:
Disulfiram induces an alcohol sensitivity that leads to a highly adverse reaction when the patient ingests even minimal amounts of alcohol. It inhibits the oxidation of alcohol at the acetaldehyde stage, causing unpleasant reactions. Additionally, disulfiram is being investigated as a potential treatment for cocaine dependence, as it prevents the breakdown of dopamine—a neurotransmitter that is released upon cocaine stimulation. The accumulation of dopamine can lead to heightened anxiety, increased blood pressure, restlessness, and other distressing symptoms.
